Pamela Bjorkman
Pamela Bjorkman
Professor Bjorkman has contributed significantly to fields and technologies converging on immune recognition of viral pathogens. She and her team are investigating the immune responses against HIV-1 and other viruses, most recently SARS-CoV-2, in order to develop improved therapeutics and/or vaccines. Applying technologies including X-ray crystallography and electron microscopy, they study pathogen glycoproteins and host immune proteins. Using structural information and alternate antibody architectures, the team is engineering antibody-based reagents with increased potency and breadth. They are also investigating the structural correlates of potent antibody-mediated neutralization of HIV-1, SARS-CoV-2, and hepatitis C virus to better understand what leads to naturally-occurring potent neutralizing antibodies. See more about this work at the Bjorkman Lab website.