2024 Caltech-City of Hope Biomedical Research Initiative Grants

Shasha Chong (CCE) & Yanzhong Yang (CoH) - Decoding TDRD3-mediated Condensates in Transcription and T cell Function

Tsui-Fen Chou (BBE), Atish Mohanty (CoH) & Ravi Salgia (CoH) - Addressing KRAS inhibitor resistance in lung cancer by single-cell proteomics: a proteomic perspective on phenotypic transformation

Julia Greer (EAS) & Ed Boas (CoH) - In situ cancer vaccination using implantable microfabricated drug dots as nucleation centers for tertiary lymphoid structures

Rustem Ismagilov (CCE) & Robert Jenq (CoH) - Tissue-infiltrating microbiome and graft-versus-host disease

Rustem Ismagilov (CCE) & Terence Williams (CoH) - Multimodal Live Imaging of a Novel siRNA Cancer Therapeutic

Stephen Mayo (BBE) & Debbie Thurmond (CoH) - Development of antigen presenting vesicles for the treatment of type 1 diabetes

Mikhail Shapiro (EAS) & Yun Rose Li (CoH) - Combining acoustic ultrasound imaging and genetically-engineered metastatic prostate cancer organoid models to enable ultra-sensitive monitoring of metastatic evolution, tumor microenvironment crosstalk and treatment response in vivo

Lihong Wang (EAS) & Yuman Fong (CoH) - Comprehensive Real-Time Imaging Surgical Platform with Energy-Transmissive Bed-Top